核心参数
仪器种类: 差示扫描量热仪
产地类别: 进口
温度范围(°C): 15–95 °C
温度准确度(℃): ±2 °C
升/降温速率( K/min): 0.01–10 °C/minute
热门推荐
让蛋白稳定性变得简单
如果能提前知道蛋白制剂的微小改动将如何影响蛋白分子的稳定性,或者提前知道蛋白分子会发生聚集,你会觉得怎么样?获取这些信息的唯一方式就是活的ΔG,而HUNK将ΔG的测定变得极为简单。你可以马上就知道蛋白结构、浓度以及制剂条件的变化将会对蛋白稳定性产生什么影响,而不是等到以后。
ΔG 定量检测蛋白稳定性
ΔGtrend 预测蛋白聚集路径
Kd 检测小分子亲和力
一切自动化
The Hunk completely automates the chemical denaturation and protein stability measurement process. Easy set up in application-specific trays is all it takes to get started. Once the Hunk gets going, it’ll crank out up to 96 ΔGs on 96 different conditions fully unattended. With those ΔGs in hand, you’ll know right away whether or not it’s worth spending your time on minimizing aggregation or optimizing solubility and viscosity.
一小时即得ΔG
The Hunk’s got a much cooler way to get ΔG values. It adds increasing concentrations of denaturant to proteins until they completely unfold to get their denaturation curves. The midpoint of the curve, the C1/2, is the concentration of denaturant needed to onehalf unfold the protein. The Hunk multiplies that C1/2 by the slope (m value) of the curve at the C1/2 to get the ΔG for each of your proteins — and does it in about an hour.
预测蛋白聚集
With one Hunk experiment, you’ll know if and how your protein could aggregate. Follow ΔG over increasing protein concentrations, and get the ΔGtrend. When ΔGtrend goes up, you might want to check out a native state aggregation fix. When ΔGtrend goes down, you’ve got denatured state aggregation to deal with. A flat ΔGtrend means you’re good to go. In one day, the Hunk gives you more info than ever before about your protein’s aggregation pathway.
仪器参数
企业名称
北京瑞德百奥生物科技有限公司
企业信息已认证
企业类型
信用代码
110106016165252
成立日期
2009-02-24
注册资本
200
经营范围
技术服务;销售化工产品、仪器仪表、机械设备、医疗器械(限Ⅰ类)、摄影器材、电子产品、文具用品;技术进出口、代理进出口、货物进出口;软件开发;设计、制作、代理、发布广告;营销策划;会议服务;企业管理咨询;工程技术咨询;城市园林绿化;投资咨询;经济信息咨询;汽车租赁。(企业依法自主选择经营项目,开展经营活动;依法须经批准的项目,经相关部门批准后依批准的内容开展经营活动;不得从事本市产业政策禁止和限制类项目的经营活动。)
北京瑞德百奥生物科技有限公司
公司地址
北京市朝阳区十里堡1号B座4013室
客服电话