TN224-01－Gilson液样平台对样品纯化后分析样品制备的自动化应用（英文）

INTRODUCTION Following successful purification of small molecule drug candidates, it is necessary to pool the fractions, dry down those pooled fractions, and then prepare samples for analysis from this dried solid. Usually, the analysis of choice is a combination of analytical LCMS and NMR. To do this, it is necessary to re-dissolve the dried solid in a known quantity of a suitable solvent and then transfer small aliquots from this sample into the appropriate analysis tubes and vials.

TN223-01－基于Gilson 223自动进样器实现牛奶铜皂法和氨基黑法检测的自动化（英文）

INTRODUCTION In laboratories specializing in milk analysis, there are two methods where Gilson could help with a semi- or full automation of the complete protocols. In comparison to the manual procedure, automation provides more robust and reproducible results and sample traceability. The first method is the Copper Soap method for the calculation of the Lipolysis Index. The second method is the Amido Black method for the calculation of protein content in milk.

TN222-01－基于Gilson GX-271液样处理平台和 UV1800紫外可见分光光度计的自动分光光度法检测的应用（英文）

INTRODUCTION A general liquid handling application is to use a liquid handler as an autosampler for a spectrophotometer. The traditional manual method for filling a flow-through cuvette is to use a peristaltic pump (a sipper) to draw the sample through the cuvette. This can easily be replicated using a Gilson GX liquid handler.

TN221-01-使用Gilson VERITY® 271 LCMS质谱引导制备色谱系统分离多肽混合物（英文）

INTRODUCTION Preparative LC coupled with mass spectrometry (MS) is a well-established method for purifying target compounds. The VERITY® 271 LCMS system (Figure 1) leverages the separating power of HPLC with the detection capabilities of MS to isolate fractions with high purity and achieve excellent recovery for target molecules. The system incorporates signal data from both ultraviolet (UV) and mass-based detectors.

TN221-01-使用Gilson VERITY® 271 LCMS质谱引导制备色谱系统分离多肽混合物（英文）

INTRODUCTION Preparative LC coupled with mass spectrometry (MS) is a well-established method for purifying target compounds. The VERITY® 271 LCMS system (Figure 1) leverages the separating power of HPLC with the detection capabilities of MS to isolate fractions with high purity and achieve excellent recovery for target molecules. The system incorporates signal data from both ultraviolet (UV) and mass-based detectors.

TN220-01-使用Gilson VERITY® 紧凑型LCMS质谱引导制备色谱系统分离多肽混合物（英文）

INTRODUCTION Liquid chromatography coupled with mass spectrometry (LCMS) is widely used in both analytical and preparative chemistry applications. In this process, compounds in a complex mixture are separated based on their size or chemical properties using LC, and the mass signal from the MS detector is used to confirm compound identity and trigger fraction collection. This mass-directed fraction collection approach allows the end user to collect fewer fractions, as compared to collecting based on UV signal alone, saving time and reducing the number of fractions that need to be dried down and processed in downstream steps of the workflow.