Agilent 1260 Infinity II 制备型液相色谱
Agilent 1260 Infinity II 制备型液相色谱
Agilent 1260 Infinity II 制备型液相色谱
Agilent 1260 Infinity II 制备型液相色谱
Agilent 1260 Infinity II 制备型液相色谱
Agilent 1260 Infinity II 制备型液相色谱

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1260 Infinity II Preparative

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欧洲

  • 钻石
  • 第22年
  • 生产商
  • 营业执照已审核
核心参数

应用级别: 实验室级别

仪器种类: 高压制备液相色谱

流速范围: 0.01-50 mL/min

流量精度: ≤0.3% RSD

流量重现性: ≤0.3% RSD

最大耐压: 420 bar

波长范围: 0.1 nm

基线噪声: 2.5 uAU

采集频率: 120Hz

安捷伦1260 Infinity II制备型液相色谱系统

简单易用的自动纯化主力系统
1260 Infinity II 制备型液相色谱系统非常适用于需要进行梯度洗脱的样品纯化。其中的钛制泵头具有耐腐蚀性和生物兼容性,利用内径为 9.4-30.0 mm 的色谱柱可为纯化过程提供最高达 50 mL/min 的流速。本系统专为常规、高通量、实验室规模的纯化过程量身打造,可用于纯化毫克级到克级的原材料。


特性:

纯化效率

  • 延迟体积降至最低,最大程度减小了峰扩散和交叉污染

  • 具有最佳的馏分体积灵活性,同时保持高精度的回收率

  • 集成且自动化的馏分延迟传感器技术,提高了所采集馏分的纯度和回收率

仪器效率

  • 流速高达 50 mL/min,可支持内径高达 30.0 mm 的色谱柱

  • 全自动化样品瓶进样器最多可容纳 120 个样品,进样量最多可达 3.6 mL

  • 每个模块可在 4 种不同外径规格的玻璃管中最多收集 216 种馏分

实验室效率

  • 通过 OpenLab CDS ChemStation 清洁软件基础架构,确保操作熟悉且可靠

  • 在相同的占地面积内可将容量扩展至最多 864 种馏分

  • 升级途径顺畅,为您的投资提供保障

  • 可扩展馏分容量,满足您的各种需求

  • Purifying a large number of compounds by liquid chromatography usually requires screening experiments and manual interaction during upscaling to preparative conditions. The Agilent Automated Purification software facilitates the workflow of analytical scouting to preparative purification by smart algorithms and calculated scale-up of separation gradients, all integrated in an intuitive interface. This Technical Overview demonstrates the purification of a compound library using the Agilent 1260 Infinity Automated LC/MSD Purification System controlled by the Automated Purification software.

    制药/生物制药 2018-09-03

  • Peak-based fraction collection triggered by a UV signal threshold leads to satisfactory results in most cases. Some samples and applications, however, require special attention when fraction collection parameters are set. This Technical Overview describes different strategies on how to achieve best collection results using different settings on an Agilent 1260 Infinity II Preparative LC/MSD System. UV and mass-based fraction collection, fraction pooling, as well as recovery collection are discussed in detail to provide knowledge that can be turned into successful and confident fraction collection.

    制药/生物制药 2018-08-27

  • Synthesizing novel compounds or isolating natural products can be a laborious and time-consuming process. After analyzing the precious sample on an analytical UHPLC system, the crucial step is to transfer the method to a preparative system with a minimal risk of losing valuable work or collecting impure compounds. This Technical Overview describes a practical way to optimize the scale-up process for reversed-phase chromatography from an analytical UHPLC system to preparative LC systems using a focused gradient to increase the sample load on the preparative column to achieve optimum purity.

    制药/生物制药 2018-09-03

  • In analytical HPLC good resolution is required over the entire gradient; in preparative HPLC it is only important to achieve good resolution around the target compound, which should be collected in highest purity. With a small set of optimized gradient methods a much better resolution can be achieved than with a single generic method. The generation of a small method set based on retention time windows in the pre-preparative analytical run is described in this Application Note. Using Agilent standards with known elution properties makes this an easy four-step process, which can be accomplished in less than one hour. An application example demonstrating how the resolution of the target compound can be improved is also shown.

    制药/生物制药 2018-09-03

  • Purifying a large number of compounds by liquid chromatography usually requires screening experiments and manual interaction during upscaling to preparative conditions. The Agilent Automated Purification software facilitates the workflow of analytical scouting to preparative purification by smart algorithms and calculated scale-up of separation gradients, all integrated in an intuitive interface. This Technical Overview demonstrates the purification of a compound library using the Agilent 1260 Infinity Automated LC/MSD Purification System controlled by the Automated Purification software.

    制药/生物制药 2018-09-03

  • Peak-based fraction collection triggered by a UV signal threshold leads to satisfactory results in most cases. Some samples and applications, however, require special attention when fraction collection parameters are set. This Technical Overview describes different strategies on how to achieve best collection results using different settings on an Agilent 1260 Infinity II Preparative LC/MSD System. UV and mass-based fraction collection, fraction pooling, as well as recovery collection are discussed in detail to provide knowledge that can be turned into successful and confident fraction collection.

    制药/生物制药 2018-08-27

  • Synthesizing novel compounds or isolating natural products can be a laborious and time-consuming process. After analyzing the precious sample on an analytical UHPLC system, the crucial step is to transfer the method to a preparative system with a minimal risk of losing valuable work or collecting impure compounds. This Technical Overview describes a practical way to optimize the scale-up process for reversed-phase chromatography from an analytical UHPLC system to preparative LC systems using a focused gradient to increase the sample load on the preparative column to achieve optimum purity.

    制药/生物制药 2018-09-03

  • In analytical HPLC good resolution is required over the entire gradient; in preparative HPLC it is only important to achieve good resolution around the target compound, which should be collected in highest purity. With a small set of optimized gradient methods a much better resolution can be achieved than with a single generic method. The generation of a small method set based on retention time windows in the pre-preparative analytical run is described in this Application Note. Using Agilent standards with known elution properties makes this an easy four-step process, which can be accomplished in less than one hour. An application example demonstrating how the resolution of the target compound can be improved is also shown.

    制药/生物制药 2018-09-03

  • 近来,水溶性维生素的分析和定量在制药领域受到越来越多的关注。反相梯度(无离子对)分离可替代常规的等度分离,能够分析包含B 族维生素、泛酸、叶酸和维生素C 等物质的8 组分样品。本研究使用 ZORBAX SB-C8 柱进行分析。

    食品/农产品 2018-11-27

  • ?This Application Note demonstrates: • Configuration of the Agilent 1200 Series Rapid Resolution LC (RRLC)analytical scale (AS) purification system. • Use of the Agilent 1200 Series RRLC AS purification system with anoptimized method for purification of peptide nucleic acids from solidphase synthesis.

    生物产业 2018-08-27

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