CS Bio Co 寡核苷酸合成仪 CS-OLIGO-D

设备应用  Device Application

设备用于研发寡核苷酸新药，寡核苷酸药物可以用于一些罕见病以及病毒引起的疾病的基因疗法。

The Device is used to develop new oligonucleotide drugs that can be used as gene therapies for some rare diseases and diseases caused by viruses.

运行原理 Principle of operation

我们的混合是将树脂悬浮在反应溶液中，并使树脂漂浮在反应瓶中。在溶液中移动的完全悬浮树脂的情况下，它将产生较高的反应和洗涤效率。

Ourmixing is to suspend the resin in the reaction solution with the resin floatingin the RV. With fully suspended resin that is moving within solution, it willyield high reaction and washing efficiency.

关键操作系统 Key System Operation

•       通过180o翻转进行混合，并从反应容器的顶部或底部鼓入氩气。

•       反应容器是由硼硅酸盐玻璃制成的开放式反应器。

•       利用冲洗流过方式进行三苯甲基脱除，在冲洗流过过程中可以进行翻转混合。

•       紫外检测器用于三苯甲基脱除。

•       氩气管路/用于维持惰性环境的反应瓶吹扫。

•       8个单独碱基储罐位（根据要求提供更多）。

•       系统可以循环。

•      Mixing is performed by 180oinversion with argon bubbling either from the top or bottom of the reactionvessel.

•      The reaction vessel is anopen reactor made of borosilicate glass

•      Flow through utilized fordetritylation, inversion mixing is possible during flow through.

•      UV detection fordetritylation

•      Argon line/reservoir purgingutilized to maintain inert atmosphere

•      8x individual amiditepositions (more at request)

•      Circulation is possible withthe system

评价 Evaluation

LCMS 分析结果   LCMS Comparison