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蛋白质药物质谱应用文集

1
应用领域: 发布时间:
2014-12-29
检测样品: 检测项目:
参考标准:
依据相关标准
浏览次数:
292
下载次数:
40 次
方案优势
The Q Exactive MS is well suited for targeted quantification providing two powerful HR/AM approaches, msx tSIM and tHCD. Both approaches demonstrate high selectivity, high sensitivity and high throughput due to several hardware and software innovations. ? For the msx tSIM approach, high mass accuracy (< 5 ppm) and high resolution (140K) ensures accurate identification of target ions in the presence of complex background, while spectrum multiplexing dramatically increases throughput without sacrificing resolution. ? A LOD of 10 amol and 4-order linear dynamic range was obtained for most peptides with msx tSIM method in the presence of medium complex background. ? Different from triple-quadrupole-based SRM, all fragment ions are simultaneously detected with high mass accuracy and high resolution using the tHCD approach. The HR/AM of fragment ions provides unmatched selectivity. The simultaneous detection of all fragment ions allows more efficient sampling of target peptides and results in improved sensitivity. A scan speed of 12 Hz at a resolution of 17,500 ensures high throughput. ? A LOD of 50 amol and 3-4 orders linear dynamic range was obtained for most peptides with tHCD method in the presence of strong complex background.
实验设备
参考报价:
面议
型号:
Q Exactive Orbitrap LCMSMS
品牌:
赛默飞
产地:
美国
关注度:
5823
完整度:
参考报价:
面议
型号:
TSQ Endura
品牌:
赛默飞
产地:
美国
关注度:
3856
完整度:
参考报价:
面议
型号:
TSQ Quantiva
品牌:
赛默飞
产地:
美国
关注度:
3346
完整度:
参考报价:
面议
型号:
Q Exactive Focus LCMSMS
品牌:
赛默飞
产地:
美国
关注度:
1619
完整度:
参考报价:
面议
型号:
LTQ Orbitrap XL
品牌:
赛默飞
产地:
美国
关注度:
5052
完整度:
大小:19M
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