Reversed-Phase Column with High Aromatic Selectivity for the Separation of Aromatic Compounds
Acclaim® Phenyl-1 columns provide unique selectivity for aromatic compounds while maintaining sufficient hydrophobic interaction and aqueous compatibility for superior chromatographic performance.
Acclaim Phenyl-1 is based on covalent modification of high-purity, spherical, porous silica particles, with a specially designed silane ligand-bearing proprietary alkyl aromatic functionality. This novel column chemistry results in the following benefits.
· High aromatic selectivity
· High hydrophobic retention
· Unique and complementary selectivity
· Compatibility with highly aqueous mobile phase
· High efficiency and rugged packing
Acclaim Phenyl-1 columns are available in 3 μm particle sizes and 4.6, 3.0, and 2.1 mm diameters, with an average pore diameter of 120 ?. Acclaim Phenyl-1 columns may be used for LC/MS applications.
Applications
The Acclaim Phenyl-1 column has a unique bonded phase which has both enhanced aromatic selectivity and high hydrophobicity compared to other commercial phenyl-type phases, including biphenyl, diphenyl, C6-phenyl and C3-phenyl phases. It is also compatible with aqueous mobile phases. These capabilities make this column ideal for a broad range of applications including drug development and testing in which analytes commonly contain rings, conjugation, and ring substituents.
| Acclaim Phenyl-1: Designed for the Analysis of Aromatic Compounds Specifications | |
|---|---|
| Column Chemistry | Proprietary alkyl phenyl |
| End-capped | Yes |
| Particle Size | 3 μm |
| Average pore diameter | 120 ? |
| Surface area | 300 m2/g |
| pH range | 2–8 |
| Temperature | <60 °C |
| Starting material | Ultrapure silica |
| Particle shape | Spherical |
| Analytical Columns | |
|---|---|
| Acclaim Phenyl-1, 3μm, Analytical, (4.6 x 150mm) | 071969 |
| Acclaim Phenyl-1, 3μm, Analytical, (4.6 x 100mm) | 078017 |
| Acclaim Phenyl-1, 3μm, Analytical, (3.0 x 150mm) | 071970 |
| Acclaim Phenyl-1, 3μm, Analytical, (3.0 x 100mm) | 074693 |
| Acclaim Phenyl-1, 3μm, Analytical, (3.0 x 50mm) | 071972 |
| Acclaim Phenyl-1, 3μm, Analytical, (3.0 x 250mm) | 074694 |
| Acclaim Phenyl-1, 3μm, Analytical, (2.1 x 250mm) | 078014 |
| Acclaim Phenyl-1, 3μm, Analytical, (2.1 x 150mm) | 071971 |
| Acclaim Phenyl-1, 3μm, Analytical, (2.1 x 100mm) | 078015 |
| Acclaim Phenyl-1, 3μm, Analytical, (2.1 x 50mm) | 078016 |
| Guard Columns | |
|---|---|
| Acclaim Phenyl-1, 3μm, Guard (4.6x10mm) | 071973 |
| Acclaim Phenyl-1, 3μm, Guard (3.0x10mm) | 071974 |
| Acclaim Phenyl-1, 3μm Guard (2.1x10mm) | 079934 |
| Acclaim SST Guard Cartridge Holder V-2 | 069580 |
| Acclaim Guard Kit (Holder and coupler) V-2 | 069707 |
| Guard to Analytical Column Coupler V-2 | 074188 |
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